Exosomes

Exosomes are nano-sized extracellular vesicles released by mesenchymal stem cells. They act as biological messengers—carrying growth factors, proteins, lipids, and genetic material (mRNA/miRNA) that facilitate communication between cells.

Rather than becoming new tissue themselves, UC-MSC exosomes signal the body to repair, regenerate, and restore function at the cellular level.

How they work:

• Modulate inflammation
• Promote angiogenesis (new blood vessel formation)
• Stimulate tissue repair and regeneration
• Support cellular communication and healing pathways

Key potential benefits in regenerative medicine:

Reduced inflammation and pain
Accelerated healing and recovery
Improved tissue quality and function
Cell-free alternative to traditional stem cell therapies
Lower immunogenicity and strong safety profile

As regenerative medicine continues to evolve, exosome-based therapies may offer clinicians a powerful, next-generation approach to treating orthopedic conditions, soft tissue injuries, and degenerative diseases.

  • What our data shows:

    1. Verified Mesenchymal Cell Profile
    Flow cytometry confirms:
    CD73+, CD90+, CD105+
    CD45−, CD34−

    This aligns with ISCT criteria for mesenchymal stem cell phenotype

    Why it matters:
    You’re not relying on assumptions—this is phenotypic confirmation of mesenchymal cells, not just “tissue claims.”

    2. High Cell Viability
    ~92% viability
    Well above industry minimums

    Why it matters:
    Higher viability = greater likelihood of biologic activity at time of use

    3. High Cell Count
    ~42 million cells per mL (lab quantified)

    Why it matters:
    Many products don’t quantify cell populations at all—this gives you a measurable biologic payload

    4. Robust Safety Testing
    14-day sterility: No growth
    Endotoxin: Within safe limits
    Full donor screening: HIV, Hep B/C, HTLV, Syphilis, etc. → Non-reactive

    Why it matters:
    This meets expectations for patient safety and clinical confidence

    5. Bioactive Growth Factor Profile
    Includes:
    VEGF (angiogenesis)
    PDGF (tissue repair)
    TGF-β1 (cell signaling)
    FGF-2, EGF (healing support)
    IL-1RA (anti-inflammatory)

    Why it matters:
    You’re delivering a biologically active environment, not just structural tissue

    This is not being positioned as a drug or cure—It is a biologic support matrix that may assist in reducing inflammation, supporting tissue healing, and enhancing the local regenerative environment.

    Especially relevant for orthopedic applications, spine procedures, and soft tissue injuries.

    If you’re looking for a well-documented, compliant biologic with transparent data—not hype—this is worth evaluating in your protocol.

  • Multilineage-Differentiating Stress-Enduring (MUSE)-derived exosomes are extracellular vesicles produced by MUSE cells that participate in cell-to-cell communication by carrying biologically active proteins, lipids, nucleic acids, and other signaling molecules.

    Our umbilical cord–derived MUSE exosome product is designed to provide the signaling component of MUSE-cell biology in a cell-free format. Rather than introducing whole cells, extracellular vesicles deliver a concentrated biological communication system capable of interacting with recipient cells and influencing cellular signaling pathways.

    MUSE cells are of particular interest in regenerative medicine because of their stress tolerance, multilineage potential, injury-responsive behavior, and paracrine activity. Their extracellular vesicles are being investigated for their ability to transfer molecular signals involved in processes such as cellular communication, inflammatory regulation, tissue protection, and repair.

    Because exosomes are cell-free, they offer a fundamentally different approach from whole-cell therapies. Research into extracellular vesicles continues to explore their potential as a mechanism for delivering biologically active cargo while avoiding the need to administer intact living cells.

    Key Characteristics

    • Umbilical cord–derived source

    • MUSE-cell-derived extracellular vesicles

    • Cell-free regenerative signaling platform

    • Naturally carry biologically active proteins, lipids, RNA, and other molecular cargo

    • Studied for intercellular communication and paracrine signaling

    • Research interest in immunomodulatory, cytoprotective, and tissue-repair pathways

    • Can be characterized using extracellular-vesicle markers such as CD9, CD63, and CD81, along with particle concentration and size distribution

    • Represents an emerging cell-free approach to regenerative medicine research

    MUSE exosomes are being investigated as a next-generation extracellular-vesicle platform for research into cellular communication, tissue repair, and regenerative biology.

Product

Exosomes: Medical Potency

125 billion | 5 ml (Back by popular demand)

MUSE Exosomes

350 billion | 1 ml

700 billion | 2 ml

BioScaffolding

1 cc BioScaffolding Matrix

2 cc BioScaffolding Matrix

*A supportive three-dimensional matrix designed to complement regenerative therapies: cellular attachment • localized signaling • tissue remodeling • regenerative applications

We offer highly competitive pricing and special considerations for first-time buyers to make it easier to experience our products’ benefits.

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